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Treatment of gestational diabetes mellitus: glyburide compared to subcutaneous insulin therapy and associated perinatal outcomes.

Promotion of health-enhancing physical activity in rheumatoid arthritis: a comparative study on healthcare providers in Italy, The Netherlands and Sweden.

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The rate of glucose production was twice as high in the diabetic subjects as in control subjects (0.

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With concomitant metformin hydrochloride tablets and sulfonylurea therapy, the desired control of blood glucose may be obtained by adjusting the dose of each drug.

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You will need to discuss the benefits and risks of taking metformin while you are pregnant.

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Do not change the dose on your own.

Usually your doctor will prescribe insulin while you are pregnant.

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Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

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Abstract OBJECTIVE: The constellation of anomalies associated with insulin resistance is a plausible additional cause of ischemic cardiovascular disease and of NIDDM.

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Drug information contained herein may be time sensitive.

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An estimated 10 million persons in the United States resemble the participants in the Diabetes Prevention Program in terms of age, body-mass index, and glucose concentrations, according to data from the third National Health and Nutrition Examination Survey.

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Metformin, which decreases hepatic glucose output and sensitizes peripheral tissues to insulin, has been shown to decrease mortality rates in patients with type 2 diabetes and is considered a first-line agent.

It is also important for your liver to be working normally when you take metformin hydrochloride extended-release tablets.

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Why is metformin used as initial therapy?

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Importantly, the percentage of TUNEL-positive cells to total cells in LV myocardium in the pacing group increased compared with that in the sham group, which was blunted by treatment with either metformin or AICAR (E).

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Unlike sulfonylureas, metformin does not produce hypoglycemia in either patients with type 2 diabetes or normal subjects (except in special circumstances, see ) and does not cause hyperinsulinemia.

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Metformin is now being studied in clinical trials for breast cancer.

It's about portion control (eating a normal portion instead of supersize portions), proper food choices, and food education.

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Metformin, courtesy of Wikimedia Commons.

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Andersson C, Olesen JB, Hansen PR, Weeke P, Norgaard ML, Jorgensen CH, et al.

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Do not breastfeed while taking Glucophage.

Therefore, in patients in whom any such study is planned, metformin hydrochloride tablets should be temporarily discontinued at the time of or prior to the procedure, and withheld for 48 hours subsequent to the procedure and reinstituted only after renal function has been re-evaluated and found to be normal.

Kidney function and age are both predictors of pharmacokinetics of metformin.

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It has been suggested that metformin could inhibit the growth of cancer cells by decreasing cellular energy status and force a metabolic conversion that cancer cells are unable to execute.

Metformin improves cardiac function in a non-diabetic rat model of post-MI heart failure.

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Following single and multiple oral doses of canagliflozin in patients with type 2 diabetes, dose-dependent decreases in RT G and increases in urinary glucose excretion were observed.

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